Laboratory guidelines for molecular diagnosis of Y-chromosomal microdeletions.
نویسندگان
چکیده
M. SIMONI, E. BAKKER, M. C. M. EURLINGS, G. MATTHIJS, E. MORO, C. R. MUÈ LLER and P. H. VOGT Institute of Reproductive Medicine of the University, MuÈnster, Germany, Department of Human and Clinical Genetics, Leiden, The Netherlands, Center for Human Genetics, University of Leuven, Belgium, Patologia Medica III, University of Padova, Italy, Institute of Human Genetics, University of WuÈrzburg, Germany, Institute of Human Genetics, University of Heidelberg, Germany
منابع مشابه
EAA/EMQN best practice guidelines for molecular diagnosis of y-chromosomal microdeletions. State of the art 2004.
Microdeletions of the Y chromosome are the second most frequent genetic cause of spermatogenetic failure in infertile men after the Klinefelter syndrome. The molecular diagnosis of Y-chromosomal microdeletions is routinely performed in the workup of male infertility in men with azoospermia or severe oligozoospermia. Since 1999, the European Academy of Andrology (EAA) and the European Molecular ...
متن کاملP-94: Male Infertility in China: Laboratory Finding for AZF Microdeletions and Chromosomal Abnormalities in Infertile Men from Northeastern China
Background: To investigate the frequencies of AZF microdeletions and chromosomal abnormalities in infertile men from Northeastern China. Moreover, to compare the prevalence of these abnormalities with other countries and regions in the world. Materials and Methods: 305 infertile men were enrolled. A complete semen analysis and reproductive hormones were measured according to standard methods. M...
متن کاملAB024. Interpretation for Y chromosomal microdeletions of EAA/EMQN 2013 guideline
After the Klinefelter syndrome, Y chromosomal microdeletions are the second most frequent genetic cause of male infertility. The European Academy Andrology (EAA) and the European Molecular genetics Quality Network (EMQN) revised the new 2014 laboratory guidelines on Sep 2013 based on 1999 and 2004 editions according to 12 years clinical accumulation and specialist consensus. The new guideline e...
متن کاملEAA/EMQN best practice guidelines for molecular diagnosis of Y-chromosomal microdeletions: state-of-the-art 2013
The molecular diagnosis of Y-chromosomal microdeletions is a common routine genetic test which is part of the diagnostic workup of azoospermic and severe oligozoospermic men. Since 1999, the European Academy of Andrology (EAA) and the European Molecular Genetics Quality Network (EMQN) have been actively involved in supporting the improvement of the quality of the diagnostic assays by publicatio...
متن کاملبررسی مولکولی حذفهای کروموزوم Y در نواحی AZF بیماران مبتلا به آزواسپرمی و اولیگواسپرمی غیر انسدادی مراجعهکننده به مرکز ناباروری منتصریه مشهد
Background and Aim: The Y-chromosome azoospermic factor (AZF) regions consist of genes whose specific roles and functions in spermatogenesis and fertility have not been completely clarified. Hence, recognition of the association between AZF microdeletions and male infertility has suggestions for the diagnosis, treatment, and genetic counseling. The main objective of the present study was invest...
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ورودعنوان ژورنال:
- International journal of andrology
دوره 22 5 شماره
صفحات -
تاریخ انتشار 1999